Glyph of Ds would be for self healing spikes when needed, but yeah it'd be rare usage,
Swap the Ghoul Major for Strangulate and and CE minor for Pestilence?
I'd keep the Raise Dead just so I don't have to have reagents for popping a ghoul out in the middle of a boss fight... so I can use the ghoul the same way I'd use my wings as a pali. short term damage booster (short term 5 mins lol).
Rotation would probably cycle IT>PS>HS>HS>OB/DS rinse and repeat, due to not having the extended diseases... though the damage increases for HS/BS/DS/OB all happen from ANY diseases on target right, cause the DK diseases don't stack I hear? In which case yeah I'd drop thew IT and PS and jsut punch out HS>HS>OB/DS>HS>HS DC when on cooldown.
I'd probably aim to gear for Hit and Haste as much as possible, rely on raid buffs to keep me over 25-30% crit.
Here's a speculation on the gear I'd aim for endgame.
Self buffed only... though I forgot to hit the unholy presence button so hit that first to see proper weapon speed.
http://www.chardev.org/?template=135249